GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs6050629 | chr20:25430680 | FAM182A | chr20:26035250-26067552:+ | -0.18 | -3.44 | 0.000635 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050629 | chr20:25430680 | FAM182B | chr20:25744102-25848786:- | 0.25 | 5.25 | 2.3E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050629 | chr20:25430680 | NINL | chr20:25433338-25566153:- | -0.34 | -7.11 | 4.29E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050629 | chr20:25430680 | PYGB | chr20:25228706-25278647:+ | -0.15 | -3.78 | 0.000174 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050630 | chr20:25430745 | ENTPD6 | chr20:25176339-25207360:+ | -0.32 | -7.43 | 5.05E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050630 | chr20:25430745 | FAM182A | chr20:26035250-26067552:+ | -0.18 | -3.44 | 0.000635 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050630 | chr20:25430745 | FAM182B | chr20:25744102-25848786:- | 0.25 | 5.25 | 2.3E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050630 | chr20:25430745 | NINL | chr20:25433338-25566153:- | -0.34 | -7.11 | 4.29E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050630 | chr20:25430745 | PYGB | chr20:25228706-25278647:+ | -0.15 | -3.78 | 0.000174 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050631 | chr20:25431749 | ENTPD6 | chr20:25176339-25207360:+ | -0.3 | -6.79 | 3.27E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050631 | chr20:25431749 | FAM182A | chr20:26035250-26067552:+ | -0.18 | -3.4 | 0.000731 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050631 | chr20:25431749 | FAM182B | chr20:25744102-25848786:- | 0.25 | 5.24 | 2.43E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050631 | chr20:25431749 | NINL | chr20:25433338-25566153:- | -0.36 | -7.3 | 1.22E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050632 | chr20:25432601 | ENTPD6 | chr20:25176339-25207360:+ | -0.32 | -7.43 | 5.05E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050632 | chr20:25432601 | FAM182A | chr20:26035250-26067552:+ | -0.18 | -3.44 | 0.000635 | Liver enzyme levels (alkaline phosphatase) |